Health Economics | Outcomes Analyst | Researcher

The Health Economics & Payer Evidence Lead (HEPEL) Anifrolumab is a lead level global role with responsibility (a) to proactively collaborate with Clinical Project, Medical Evidence and Observational Research, and Payer Teams in designing and implementing innovative health economic and payer evidence strategies and activities and (b) to produce scientific payer evidence for Global Reimbursement Dossiers (GRD), payer submissions and market access, with focus on Anifrolumab.

The job holder will have an in-depth, expert technical knowledge and tactical experience of health economics and payer evidence (including analytic techniques and tools such as clinical trial design and analyses, systematic literature reviews, comparative effectiveness/indirect comparisons, health economic modelling and large data sets), and its application to pharmaceutical development throughout the development process. The incumbent is expected to have the ability to work independently, understand and apply different technical approaches, and have wide understanding of different health care systems, as well as significant experience in global payer evidence development and delivery.

Accountabilities:

• High quality health economics and payer evidence input in to pharmaceutical development projects, payer evidence plans, and market access & pricing strategies
• Proactively and independently contribute to project planning processes and help predict and resolve issues that affect market access decisions
• Detailed strategic and tactical planning of payer analytics (including clinical trial design and analysis, economic modelling, systematic reviews, and comparative effectiveness including indirect treatment comparisons) to support market access and reimbursement for assigned projects
• Assume, as a member of a team, delivery of health economics and payer evidence related activities, and contribute to or lead work streams
• Represent health economics and payer evidence in interactions with cross-functional team members at a project level, including input to clinical trial and program design, patient reported outcomes (PROs) and real-world evidence (RWE) to support payers’ needs
• As required, represent the payer perspective on the labeling and regulatory activities team
• Deliver clear, customer-focused and robust Global Reimbursement Dossiers
• Application of expert quantitative skills to support value demonstration and commercialization of products including through Health Technology Assessment (HTA)
• Provide expert quantitative thinking to support interpretation and decision-making processes
• Network with colleagues and experts, providing consultancy in own area of expertise and serving as a resource for others by sharing experience within and beyond project team and GPEP/OPEP function
• Collaborate with marketing companies in preparing evidence that satisfies payer requirements
• Generate peer reviewed scientific publications, as well as effective communication of complex ideas for use with both payers and other stakeholders
• Prepare proposal requests for outsourced health economics / payer evidence projects and manage the vendor selection process
• Deliver assigned projects to time, budget, and quality, including the management of vendors as required
• Participate in external health economics, payer evidence and analytic departmental activities via technical presentations, committee membership, publication reviews, and other similar activities
• Actively monitor and apply new analytical techniques and payer evidence trends
• Interact with health technology appraisal authorities and advisors/key external experts in preparing materials for scientific advice or reimbursement submissions

Required:

• Bachelors degree in biomedical science, business, quantitative disciplines or economics.
• In-depth expert knowledge and technical capability in health economics and payer evidence needs, and its application to pharmaceutical development at an international level, especially economic modelling, evidence synthesis and other analytical techniques required to support payer needs.

Preferred:

• Formal post graduate degree in health economics or a related quantitative discipline, or substantial work experience in the discipline.
• Payer launch experience at a local or global level (desirable).

Skills and Capabilities

• Recognized internally as the ‘go to’ expert in making connections between facts, data and trends across multiple and complex projects, developing longer-term objectives that have a positive impact on the business and are based on what is likely to happen in the future.
• Influences cross functionally and senior stakeholders by thinking more broadly and anticipating the future.
• Proactive application of therapeutic area and disease treatment knowledge.
• Builds and develops strong relationships, engaging individuals, teams and networks cross-functionally and across geographies to deliver change and positive organisational impact.
• Successfully drives and leads work cross-functionally and cross-geographies. Applies knowledge and experience of diversity to take advantage of opportunities and to mitigate challenges in order to deliver results successfully.
• Recognized internally as, the ‘go to’ expert in written and verbal communications, leveraging a range of communications tools and techniques in any situation both internally and externally, to drive and lead achievement of business results.
• Is guided by a range of considerations in deciding the best course of action in influencing internal and external stakeholders, including payers (e.g. cultural, personal relationships, personal impact and hierarchical positions).
• Demonstrates robust awareness of cross function resource necessary to deliver projects, and puts in place realistic plans based on these resource requirements to deliver results to the business.
• Proactively engages customers and/or stakeholders in the development or identification of solutions, seeking to understand and resolve underlying issues or needs.
• Seeks efficiencies, developing strategic partnerships, and negotiation/challenge with vendors on speed and budget.

Technical Capabilities

• Proactively brings payer analytic and evidence expertise and insight to the cross-functional development of future-focused, customer-driven payer evidence strategy to inform key AstraZeneca processes and decision points.
• Informs the direction of payer evidence strategy and planning, championing future-focused thinking, compelling payer insights and innovative ideas.
• Demonstrates deep insight into the wider market and competitor activity across own therapy area, additional therapy areas and across franchises.
• Works with teams to develop value propositions and pricing & market access strategy.
• Understands diverse pricing and reimbursement processes in order to maximize reimbursement opportunities through appropriate and timely payer evidence generation and analytics.
• Proactively applies therapeutic area and disease treatment knowledge in to analytics to maximize payer outcomes.
• Handles unforeseen circumstances and actively monitors and applies new analytical techniques.
• Takes a holistic view of the evidence exploration process, knowing exactly how to respond to unpredictable circumstances caused by data gaps, unexpected results or the introduction of new unforeseen external data which may require model paradigm shifts.
• Actively seeks out, assesses and applies where appropriate newly published analytical techniques relevant to evidence exploration.
• Distills complex technical data and reports into effective messaging so that the value and reach is maximized across cross-functional stakeholders.
• Ensures that the evidence needs of payers have been incorporated into the development plan (including RWE and PROs) and that the reimbursement and pricing risks are understood by the payer, regulatory, medical evidence and clinical teams.
• Ensures that appropriate payer analyses are planned and delivered in a timely manner to support reimbursement submissions.
• Proactively applies therapeutic area and disease treatment knowledge in to study design and analysis to maximise payer outcomes, experience in Immunology is desirable.
• Demonstrates an in depth and practical understanding of innovative study methodologies, including analyses, that incorporates clinical, medical, regulatory, commercial, payer and health technology assessment needs.
• Anticipates future requirements to shape the clinical and medical development plan with different options.