Here are sample job postings for Biochemist / Biophysicist roles...


Biochemist / Biophysics Scientist

SAIC

Virginia•Remote

SAIC is currently seeking Biological and/or Chemical Detection support with a background or experience in food, agricultural, and veterinary defense (FAVD) for Research and Development (R&D) efforts under Department Homeland Security Counter Weapons of Mass Destruction (DHS CWMD). This position can be worked 100% remote nationwide.

The ideal candidate will have an extensive background in one or more of the following fields of study: animal science, veterinary science, pathogen diagnostics, biology, biophysics, biochemistry, biomedical engineering, or Select Agents and Toxins. The successful candidate will have biological subject matter expertise and be able to provide technical support with knowledge of methods for searching, collecting, and collating information. Duties and responsibilities include research and development as it relates to materiel solutions in support of the DHS mission, Program Management Office (PMO) support, interacting with government, academic, and private industry representatives, as well as National Laboratories and other SMEs, engineers, and support staff within CWMD.

Duties and Responsibilities:

  • Provide technical support with knowledge of methods for searching, collecting, and collating information
  • Knowledge or direct experience in biological detection techniques and principles, such as immunological, molecular, field-forward, and laboratory-based
  • Advise CWMD Research & Development (R&D) division on R&D technologies, studies, and programs related to detection of chemical weapons of mass destruction
  • Detailed note-taker, capable of recording clear minutes, decision points, and/or action items during meetings.
  • Generate, edit, and interpret scientific reports based upon technical results from CWMD research and development efforts
  • Serve as a technical expert working with the federal staff to assist in development of forward-focused plans, acting in an advisory & assistance services (A&AS) capacity
  • Ability to conduct in-depth literature searches using publicly available information search and gathering tools and the DHS library (once trained)
  • Ability to collect information, digest the information, and place in reports and documents with minimal supervision

Qualifications

  • Bachelor’s degree and at least 3 years of experience
  • Must be a US Citizen
  • Must have an active Secret clearance with ability to eventually obtain SCI
  • Experience and background in animal science, veterinary science, biology, biophysics, biochemistry, biomedical engineering, and/or biological detection technologies
  • Prior project or program management support experience a plus
  • Must be able to initiate, supervise, develop requirements for projects from inception to conclusion
  • Detailed note-taker, capable of recording clear minutes, decision points, and/or action items during meetings.

Desired Qualifications:

  • Knowledge and experience in animal science, veterinary science, biology, biophysics, biomedical engineering, biological detection technologies
  • Knowledge or direct experience in biological detection techniques and principles, such as immunological, molecular, field-forward, and laboratory-based
  • Characterization or testing (field or laboratory) of prototype biological detectors and systems
  • Familiarity with instrumentation development and data analysis
  • Familiarity with bioinformatics including National Center for Biotechnology Information (NCBI) GenBank and/or European Molecular Biology Laboratory (EMBL)
  • Familiarity with fielded biological detection systems; Knowledge of current baselines and standard technology

Manufacturing Biochemist

infosoft

Newark, DE 19702

This position is for the Healthcare Diagnostics division.

Job Description:

  • This role is for a person to engage as part of a team with Clients-Healthineers staff to participate in the transfer of new clinical chemistry and immunoassay products from R&D into manufacturing.
  • This role will require the ability to develop an understanding of the critical quality aspects of the biological products the design of which is to be transferred into manufacturing as well as the details of the manufacturing system used.
  • This will entail working closely with an internal team to understand the components of the products and assisting in the documentation to enable the procurement, receipt, and testing of those components and the establishment of a bill of materials for the products in an SAP-based ERP system.
  • It will also entail working closely with various functions (operations, procurement, manufacturing planning, quality assurance, process engineering, etc.,) in the manufacturing plant to help establish the process/workflow for the manufacture of the product, help author the validation plans for the processes established and to help author the operating instructions, worksheets and other documentation as necessary to produce the product.
  • The successful candidate should have the knowledge &/or experience with chemical/biochemical processes and ideally clinical diagnostic products and operating in an FDA-regulated environment.
  • It is preferred, but not required, that the candidate have prior experience with standards and calibrator products used in the clinical diagnostics industry, and have experience or familiarity with managing the support of commercial products.

Key aspects will likely include exposure or the ability to directly support the following objectives:

  • Evaluation of process equipment to produce custom-formulated liquid reagents as well as automated material handling equipment to label and package the final product
  • Physical/chemical characterization of product, metrology, performance testing, and working with the team to correlate the impact of process parameters on the end-use product.
  • Documentation of processes, validations, and authoring technical protocols, reports, and testing procedures in a regulatory-compliant environment.
  • Development of/or management of external partners that may produce critical raw materials
  • Interpreting analysis of instrument-chemistry interactions for clinical chemistry methods to understand sensitivities of product to manufacturing processes.
  • Lead and conduct troubleshooting activities as necessary to determine the root cause for failures and identify and verify corrective actions.
  • Must be familiar with the design change, design verification, and validation requirements for products and processes.
  • Should be able to plan and execute assay verification and validation studies
  • The position will be as an individual contributor – no personnel management experience is required, however, it is expected that the person will have excellent oral and written communication skills and be able to effectively function as part of a broad cross-functional team.

Essential Knowledge, Skills and Abilities, Preferred Education, Experience:

  • Bachelor’s degree is required but advanced degreed candidates and those with sufficient directly relevant experience are strongly preferred.
  • The technical focus should be on Biochemical Engineering, Biochemistry, or Chemical Engineering.
  • Other disciplines may be considered for candidates with extensive design transfer and/or process experiences.
  • Applied knowledge and at least 3 years of direct experience are preferred in the development of manufacturing processes for biochemical reagents and/or pharmaceuticals.
  • Specific experience in the manufacture of products used in clinical diagnostics is preferred.
  • Project Management training and experience are a plus
  • Should be knowledgeable about FDA and other external regulatory agency requirements including cGMP, familiar with safety aspects of biohazardous materials; provide technical support for regulatory submissions/registrations.

Additional relevant technical experiences may include:

  • Biochemical/chemical manufacturing experience, fluid process design (precision dispensing/filling equipment, mixing, filtering, etc.,) fluid test/analysis methodologies (conductivity, flow, IR, HPLC, etc.,), electrochemistry/electrochemical sensor manufacture, tableting, physical pharmacy,
  • Experience in experimental design, use of DOE, and statistical analysis software is a plus. Knowledge of statistical Process Control is necessary.
  • Relevant work experiences may include In-vitro diagnostic or pharmaceutical product manufacture.
  • manufacturing, compounding, and processing of pharmaceuticals,
  • Apply scientific and statistical principles and provide technical leadership to perform a wide variety of technical investigations arising out of reagent performance issues encountered during reagent manufacturing. Working knowledge of clinical chemistry and application of automated assays in clinical chemistry laboratories.
  • Ability to build strong working relationships in cross-functional project teams to develop technical solutions to problems

Senior Protein Biochemist

Draper

Cambridge, MA

Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 1,800 employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com.


Our work is very important to us, but so is our life outside of work. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities. If this specific job opportunity and the chance to work at a nationally renowned R&D innovation company appeals to you, apply now www.draper.com/careers.


Equal Employment Opportunity

Draper is committed to creating a diverse environment and is proud to be an affirmative action and equal opportunity employer. We understand the value of diversity and its impact on a high-performance culture. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity, national origin, veteran status, or genetic information.


Draper is committed to providing access, equal opportunity and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation, please contact hr@draper.com.

Responsibilities

The Bioengineering Division is seeking a Senior Research Scientist to join a team developing cutting-edge biotechnological solutions for our Synthetic Biology R&D program area, working in a new and expanded 13,000 square foot BSL-2 laboratory in our Kendall Square location. The ideal candidate will be fluent in protein biochemistry, with background and experience working with various classes of proteins. This technical position requires bench work as well as collaborating with multidisciplinary teams to analyze experimental results, present findings, and brainstorm new ideas. The position also requires teamwork, tenacity and attention to detail. We offer an atmosphere that fosters innovation, a supportive team environment, intellectual freedom and creativity, and an emphasis on career development.


Qualifications

Required:

  • Ph.D. in Biochemistry, Analytical Chemistry, or a related biological science field, with 5+ years of research expertise in protein biochemistry (including mutagenesis, expression, and purification strategies)
  • Experience with troubleshooting and optimizing protein expression, solubility, and stability
  • Expertise with a range of analytical techniques in protein biochemistry
  • Experience in protein modeling and protein structure-function analysis and software
  • Interest in collaboration with multidisciplinary teams, and willingness to brainstorm in topics outside your area of research
  • Ability to work independently, but as part of a wider team
  • Willingness to mentor both senior and junior research colleagues
  • Excellent communication, presentation and organizational skills
  • Interest in writing proposals/grants and participating in the formation of new programs to solve the nation’s most challenging problems


Preferred:

  • Demonstrated ability to communicate ideas in proposal/grant formats



Research Scientist Protein Biochemist

Dartmouth College

Hanover, NH

Position Purpose

The Dartmouth Institute for Biomolecular Targeting (bioMT) is seeking an experienced staff member to join its Core Facilities (Molecular Tools Core and Molecular Interactions and Imaging Core). The successful applicant will possess knowledge and hands-on experience on the design, production, and biophysical characterization of recombinant proteins. The Protein Biochemist will employ high-throughput approaches for construct design and protein expression and develop purification workflows involving multiple chromatographic methods (e.g., AP, IEC, SEC). Previous experience with structural analysis (x-ray, or cryoEM) of proteins and/or in proteomics will be highly desirable. This person will actively contribute to and facilitate multidisciplinary research projects across the Dartmouth community. Other activities include but are not limited to, data collection and reporting, equipment maintenance, and training of bioMT investigators.


Description
Required Qualifications - Education and Yrs Exp

PhD or equivalent combination of education and experience


Required Qualifications - Skills, Knowledge and Abilities

  • High competency in basic laboratory skills (pipetting, weighing, sterile technique, and recordkeeping), molecular cloning, and one or more of bacterial, insect, or mammalian cell culture.
  • Experience with protein purification methods and equipment.
  • Ability to learn, develop, and apply new techniques.
  • Ability to work independently and apply critical thinking and sound judgment.
  • Good organizational and time management skills.
  • Ability to multitask.
  • Ability to draft clear technical protocols.
  • Willingness to work with hazardous materials including biological agents and/or hazardous chemicals.
  • Knowledge of computers and software applications.
  • Excellent communication skills.
  • Willingness to work closely with diverse groups of students and research staff, including the ability to manage and resolve conflicts.


Preferred Qualifications

Four+ years of relevant research experience or the equivalent work in a laboratory is highly desirable